Effect of vagal nerve stimulation in a case of Tourette's syndrome and complex partial epilepsy
Identifieur interne : 003460 ( Main/Exploration ); précédent : 003459; suivant : 003461Effect of vagal nerve stimulation in a case of Tourette's syndrome and complex partial epilepsy
Auteurs : Alan Diamond [États-Unis] ; Christopher Kenney [États-Unis] ; Joseph Jankovic [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-08.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Complex partial epilepsy, Electric Stimulation Therapy, Epilepsy, Complex Partial (complications), Epilepsy, Complex Partial (therapy), Gilles de la Tourette syndrome, Humans, Male, Nervous system diseases, Tic, Tics, Tics (physiopathology), Tourette Syndrome (physiopathology), Tourette Syndrome (therapy), Tourette's syndrome, VNS, Vagus Nerve, vagal nerve stimulation.
- MESH :
- complications : Epilepsy, Complex Partial.
- physiopathology : Tics, Tourette Syndrome.
- therapy : Epilepsy, Complex Partial, Tourette Syndrome.
- Adult, Electric Stimulation Therapy, Humans, Male, Vagus Nerve.
Abstract
We report on a 30‐year‐old man with Tourette's syndrome (TS) and medication‐refractory epilepsy whose tics improved after implantation of a vagal nerve stimulator (VNS). To verify the patient's observation, we performed a blinded video assessment using the modified Rush video‐based tic rating scale. The patient underwent two separate video recordings (VNS on and VNS off). A rater, blinded to patient's VNS status, evaluated the videos with the modified Rush video‐based tic rating scale. There were improvements in total tic score and motor and phonic tic frequency. If verified by controlled clinical trials, this observation may provide insights into the pathophysiology of tics and may lead to a novel therapy for patients with severe TS. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20949
Affiliations:
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To verify the patient's observation, we performed a blinded video assessment using the modified Rush video‐based tic rating scale. The patient underwent two separate video recordings (VNS on and VNS off). A rater, blinded to patient's VNS status, evaluated the videos with the modified Rush video‐based tic rating scale. There were improvements in total tic score and motor and phonic tic frequency. If verified by controlled clinical trials, this observation may provide insights into the pathophysiology of tics and may lead to a novel therapy for patients with severe TS. © 2006 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li></region><settlement><li>Houston</li></settlement><orgName><li>Baylor College of Medicine</li></orgName></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Diamond, Alan" sort="Diamond, Alan" uniqKey="Diamond A" first="Alan" last="Diamond">Alan Diamond</name></region><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><name sortKey="Kenney, Christopher" sort="Kenney, Christopher" uniqKey="Kenney C" first="Christopher" last="Kenney">Christopher Kenney</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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